ABSTRACT Purpose: Cystic breast lesions are a common finding in young as well as elderly females.Although, mostly benign; they can at times be malignant too.Timely diagnosis is possible with help of Fine needle aspiration cytology (FNAC).This study was carried out with the aim of studying the panorama of various cystic breast lesions on FNAC in our
Non-uniform shortening of the action potential duration (APD90) in different myocardial regions upon heart rate acceleration can set abnormal repolarization gradients and promote arrhythmia.This study examined whether spatial heterogeneities in APD90 restitution can be amplified by drugs with clinically proved proarrhythmic potential (dofetilide, q
Mycobacterium tuberculosis synthesises isoprenoid precursors via the MEP/DOXP pathway and at least five enzymes in the pathway (Dxs1, Dxr/IspC, IspD, IspF, and GcpE/IspG) are required for growth in vitro.We investigated the role of LytB (IspH) in M.tuberculosis; M.tuberculosis is unusual in that it has two homologs-LytB1 and LytB2.We were unable to
Abstract Background Most primary Triple Negative Breast Cancers (TNBCs) show amplification of the Epidermal Growth Factor Receptor (EGFR) gene, leading to increased protein expression.However, unlike other EGFR-driven cancers, targeting this receptor in TNBC yields inconsistent therapeutic responses.Methods To elucidate the underlying mechanisms of